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MTHFR is a critical enzyme in the body. It helps metabolic processes that repair DNA and switches our genes on and off as well as helping to convert folate and folic acid – each a form of Vitamin B9 – into the biologically active form called L-methylfolate (or 5-MTHF). The MTHFR gene provides the instructions for making that MTHFR enzyme and variations in the MTHFR gene may therefore affect enzyme function. This simple buccal swab test identifies the genetic variations related to the C677T and A1298C Single Nucleotide Polymorphisms (SNPs), that have been shown to influence levels of homocysteine levels, which can be a risk factor for other diseases and health issues.